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pig Why do pores become clogged in the first place? Copy Copy

pig bio Pores clog because skin cells lining the follicle shed abnormally, stick together and mix with sebum to form a plug instead of exiting the pore. This process, called follicular hyperkeratinization, is driven by androgens, low linoleic acid in sebum and interleukin-1α signalling, which is why retinoids that normalize cell turnover are first-line acne treatments.

pig Why do pores become clogged in the first place? Copy Copy

pig bio Pores clog because skin cells lining the follicle shed abnormally, stick together and mix with sebum to form a plug instead of exiting the pore. This process, called follicular hyperkeratinization, is driven by androgens, low linoleic acid in sebum and interleukin-1α signalling, which is why retinoids that normalize cell turnover are first-line acne treatments.

pig What actually causes acne, and how does a pimple form? Copy Copy

pig bio Acne forms when excess sebum, dead skin cells and Cutibacterium acnes bacteria block a hair follicle and trigger inflammation. The clogged follicle (microcomedo) grows into a visible comedo, then becomes an inflamed papule or pustule once the immune system reacts to trapped bacteria and lipids.[1]

pig What actually causes acne, and how does a pimple form? Copy Copy

pig bio Acne forms when excess sebum, dead skin cells and Cutibacterium acnes bacteria block a hair follicle and trigger inflammation. The clogged follicle (microcomedo) grows into a visible comedo, then becomes an inflamed papule or pustule once the immune system reacts to trapped bacteria and lipids.[1]